<samp id="fbtor"><video id="fbtor"></video></samp>
  • <small id="fbtor"></small>
    <ruby id="fbtor"></ruby>
    <ruby id="fbtor"><video id="fbtor"></video></ruby>
  • <ruby id="fbtor"><table id="fbtor"><b id="fbtor"></b></table></ruby>

    <track id="fbtor"><table id="fbtor"></table></track>
      <strong id="fbtor"></strong> <legend id="fbtor"><font id="fbtor"></font></legend><strong id="fbtor"></strong>
      1. <small id="fbtor"></small>

        關(guān)于參與申報2021年度湖北省科技進(jìn)步獎的公示

        關(guān)于參與申報2021年度湖北省科技進(jìn)步獎的公示

        項目名稱(chēng):基于食藥同源功效成分制備關(guān)鍵技術(shù)開(kāi)發(fā)與特膳食品創(chuàng )制

        提名獎種:湖北省科技進(jìn)步獎

        提名單位:湖北省教育廳

         

        項目簡(jiǎn)介:項目依托湖北中醫藥大學(xué)藥食兩用資源開(kāi)發(fā)湖北省工程技術(shù)中心,湖北工業(yè)大學(xué)生物工程與食品學(xué)院,教育部微生物發(fā)酵重點(diǎn)實(shí)驗室,寶得瑞健康產(chǎn)業(yè)有限公司(北京寶得瑞食品有限公司)、完美(廣東)日用品有限公司等單位,從2004年以來(lái),開(kāi)展傳統中草藥(藥材)、食藥兩用資源中生物活性成分降糖降脂、抗疲勞、耐缺氧、抗氧化、抗輻射等基礎與應用研究;生物活性成分通過(guò)調節腸道菌群影響機體糖脂代謝研究,生物活性成分沙棘原花青素、多糖提取、分離及特膳食品配料南瓜粉、沙棘粉制備關(guān)鍵技術(shù)及裝備研究,為基于藥食同源功效成分作用機制的特膳食品開(kāi)發(fā)做了大量基礎性研究及產(chǎn)業(yè)化實(shí)施工作,開(kāi)發(fā)出等一系列康養食品,取得良好的經(jīng)濟與社會(huì )效益。

         

        主要完成單位:

        序號

        單位名稱(chēng)

        1

        湖北中醫藥大學(xué)

        2

        湖北工業(yè)大學(xué)

        3

        寶得瑞(湖北)健康產(chǎn)業(yè)有限公司

        4

        北京寶得瑞健康產(chǎn)業(yè)有限公司

        5

        完美(廣東)日用品有限公司

         

        主要完成人及貢獻:

        序號

        姓名

        對項目的創(chuàng )造性貢獻

        1

        李  瑋

        抗氧化食品功效成分提取分離、納米包埋穩態(tài)化處理研究;闡釋高原口糧等特膳食品原料多菌種發(fā)酵對風(fēng)味的影響;研發(fā)霧化噴涂技術(shù)、液態(tài)油脂預包埋技術(shù),使產(chǎn)品質(zhì)地硬度、結構均一性、連食性能得到顯著(zhù)改善。

        2

        李德遠

        構建了高原口糧能量與營(yíng)養的雙源(糖源+氮源)梯度供給模式,實(shí)現能量與營(yíng)養的均勻輸出。

        3

        譚志超

        沙棘原花青素制備、原花青素高聚體和低聚體的分離方法。

        4

        李曉敏

        建立了規?;a(chǎn)的技術(shù)規程和部分特膳食品產(chǎn)品標準。

        5

        劉洪濤

        從腸道微生物菌群調控,代謝組學(xué)分析等多維度,闡釋消渴苷食藥同源功效成分對腸道微生物影響及降糖機制研究。

        6

        羅會(huì )兵

        創(chuàng )制了GI55特膳食品。

        7

        王輝斌

        南瓜全粉加工研究,沙棘粉制備技術(shù)及裝備研發(fā)。

        8

        王大鵬

        管道化生產(chǎn)的南瓜粉及其制備方法,分離沙棘籽、皮、汁的加工方法,二氧化碳萃取沙棘籽油技術(shù)。

        9

        張存存

        部分特膳食品創(chuàng )制。

        10

        吳慧清

        南瓜消渴苷功效成分提取分離,降糖降脂效應與作用機制。

        11

        李玟君

        建立了抗氧化功效成分及葛根有效成分提取分離新方法。

        12

        楊芳

        闡釋南瓜消渴苷降糖降脂功效關(guān)系。

        13

        萬(wàn)方云

        降糖產(chǎn)品創(chuàng )制。

        14

        張德新

        山藥功效成分提取分離研究。

        15

        馬芝麗

        苦瓜功效成分提取分離研究。

         

        主要知識產(chǎn)權目錄:

        序號

                    名稱(chēng)

        專(zhuān)利號

        類(lèi)型

        狀態(tài)

        1

        一種抗四氧化二氮的應激食品及制備方法

        ZL201410826339.7

        發(fā)明

        已授權,有效

        2

        一種管道化生產(chǎn)的南瓜粉及其制備方法

        ZL200510086663.0

        發(fā)明

        已授權,有效

        3

        一種南瓜全粉及其制備方法

        ZL200910311045.x

        發(fā)明

        已授權,有效

        4

        一種酶解工藝生產(chǎn)南瓜全粉的方法

        ZL201310306131.8

        發(fā)明

        已授權,有效

        5

        一種南瓜全粉的制備方法

        ZL201110095274.x

        發(fā)明

        已授權,有效

        6

        一種沙棘粉的制備方法及其生產(chǎn)設備

        ZL200510115389.5

        發(fā)明

        已授權,有效

        7

        一種分離沙棘果籽、皮、汁的加工裝置和方法

        ZL201310304563.5

        發(fā)明

        已授權,有效

        8

        一種沙棘籽超臨界二氧化碳萃取方法

        ZL201410057681.5

        發(fā)明

        已授權,有效

        9

        一種提取沙棘籽中原花青素的方法

        ZL201110367195.x

        發(fā)明

        已授權,有效

        10

        一種低溫低能耗高效率提取沙棘籽中原花青素的方法

        ZL201610015154.7

        發(fā)明

        已授權,有效

        11

        一種從脫脂沙棘籽中分離原花青素高聚體和低聚體的方法

        ZL201510013567.7

        發(fā)明

        已授權,有效

        代表性論文目錄:

        (1)Wei Li , Yong Shi ,Yong Hu , Ning Xu,Dongsheng Li,Chao Wang and Deyuan Li * Study on condition of Ultrasound-assisted Thermo-alkali-modified Peanut Protein Embedding Curcumin for Nanoparticles Journal of Food Science and Technology,2020 57:1049–1060. (IF=1.95)

        (2)Wei Li, Mengzhou Zhou, NingXu, Yong Hu, Chao Wang, Deyuan Li, Lie gang   Liu,Dongsheng Li*.Comparative analysis of protective effects of curcumin,curcumin-p-cyclodextrin nanoparticle and nanoliposomal curcumin on unsymmetricaldimethyl hydrazine poisoning in mice, Bioengineered.2016,7(5):334-341. (IF=2.2)

        (3)Wei Li,Shugang Li,Chao Wang, Yong Hu,Mengzhou Zhou,Dongsheng Li, Deyuan   Li* Impact of hot alkali modification conditions on secondary structure of peanut protein and embedding rate of curcumin,Food Science and Human Wellness, 2019, 8(3): 283-293 (IF=2.46)

        (4) Haidong Wang,Deyuan Li,Wei LI*.Protective effects of green tea polyphenol aginst renal injury through ROS –mediated JNK-MAPK pathway in lead exposed rats,Molecules and Cells,2016,39(6):508-513. (IF=4.08)

        (5) Zhi Li Ma,DeYuan Li*Separation, Identification, and Antioxidant Activity of Polyphenols from Lotus Seed Epicarp,Molecules,2019,11 (IF=3.26)

        (6) Wenjun Li,Ning Xu, Yong Hu, Zhijie Liu, Wei Li* and Deyuan Li*.Protective Effects of Flavonoid and Polyphenol from Lotus Leaf on Lung Damage Induced by Inhalation of N2O4 in mice. E3S Web of Conferences 233, 02013 (2021)(EI)

        (7) DeYuan Li,Protective Effects of Metallothionein -β-cyclodextrin Nanoparticle and Liposome-carried Metallothionein on Dinitrogen Tetroxide Poisoning Mice ,Proceedings of International Conference on Biotechnology and Medical Engineering,2019,11(EI)

        (8) Bao, Aizhen Lin, Hongtao Liu*. Chitosan Oligosaccharides attenuate loperamide-induced constipation through regulation of gut microbiota in mice. Carbohydr Polym, 2020, doi.org/ 10.1016/j.carbpol.2020.117218 (IF=7.18).

        (9)Xue Cheng, Junping Zheng, Aizhen Lin, Hui Xia, Zhigang Zhang, Qinghua Gao, Wenliang Lv*, Hongtao Liu*. A review: roles of carbohydrates in human diseases through regulation of imbalanced intestinal flora. J Funct Foods, 2020; 74: 104197 (IF=3.70).

        (10)Baifei Hu, Cheng Ye, Elaine Lai-Han Leungc, Lin Zhu, Haiming Hu, Zhigang Zhang, Junping Zheng*, Hongtao Liu*. Bletilla striata oligosaccharides improve metabolic syndrome through modulation of gut microbiota and intestinal metabolites in high fat diet-fed mice. Pharmacol Res, 2020; 159: 104942 (IF=5.89).

        (11)Lin Zhu, Baifei Hu, Yanlei Guo, Huabing Yang, Junping Zheng, Xiaowei Yao, Haiming Hu*, Hongtao Liu*. Effect of Chitosan oligosaccharides on ischemic symptom and gut microbiota disbalance in mice with hindlimb ischemia. Carbohydr Polym, 2020; 240: 116271 (IF=7.18).

        (12)Haiming Hu, Aizhen Lin, Mingwang Kong, Xiaowei Yao, Mingzhu Yin, Hui Xia, Jun Ma*, Hongtao Liu*. Intestinal microbiome and NAFLD: molecular insights and therapeutic perspectives. J Gastroenterol, 2020; 55(2): 142-158 (IF=6.13).

        (13)Junping Zheng, Jing Zhang, Yanlei Guo, huabing Yang, Aizhen Lin, Baifei Hu, Qinghua Gao, Yunzhong Chen*, Hongtao Liu*. Improvement on metabolic syndrome in high fat diet-induced obese mice through modulation of gut microbiota by Sangguayin decoction. J Ethnopharmacol, 2020; 246: 112225 (IF=3.69).

        (14)Xubing Yuan, Junping Zheng, Siming Jiao, Gong Cheng, Cui Feng, Yuguang Du*, Hongtao Liu*. A review on the preparation of chitosan oligosaccharides and application to human health, animal husbandry and agricultural production. Carbohydr Polym, 2019; 220: 60-70 (IF=7.18).

        (15)Junping Zheng, Lin Zhu, Baifei Hu, Xiaojuan Zou, Haiming Hu, Zhigang Zhang, Nan Jiang, Jun Ma, Huabing Yang*, Hongtao Liu*. 1-Deoxynojirimycin improves high fat diet-induced nonalcoholic steatohepatitis by restoring gut dysbiosis. J Nutr Biochem, 2019; 71: 16-26 (IF=4.87).

        (16)Yibo Bai, Junping Zheng, Xubing Yuan, Siming Jiao, Cui Feng, Yuguang Du*, Hongtao Liu*, Lanyan Zheng*. Chitosan oligosaccharides improve glucolipid metabolism disorder in liver by suppression of obesity-related inflammation and restoration of peroxisome proliferator-activated receptor gamma (PPARγ). Mar Drugs, 2018; 16(11). pii: E455 (IF=4.07).

        (17)Junping Zheng, Xubing Yuan, Gong Cheng, Siming Jiao, Cui Feng, Xiaoming Zhao, Heng Yin, Yuguang Du*, Hongtao Liu*. Chitosan oligosaccharides improve the disturbance in glucose metabolism and reverse the dysbiosis of gut microbiota in diabetic mice. Carbohydr Polym, 2018; 190: 77-86 (IF=7.18).

        (18)Junping Zheng, Gong Cheng, Qiongyu Li, Siming Jiao, Cui Feng, Xiaoming Zhao, Heng Yin, Yuguang Du*, Hongtao Liu*. Chitin oligosaccharide modulates gut microbiota and attenuates high-fat-diet-induced metabolic syndrome in mice. Mar Drugs, 2018; 16 (2). pii: E66 (IF=4.07).

        (19)Yu Li, Hongtao Liu#, Qingsong Xu, Yuguang Du, Jian Xu. Chitosan oligosaccharides block LPS-induced O-GlcNAcylation of NF-κB and endothelial inflammatory response. Carbohydr Polym, 2014; 99: 568-78 (IF=7.18).

        (20)Hongtao Liu, Pei Huang, Pan Ma, Qishun Liu, Chao Yu, Yuguang Du. Chitosan oligosaccharides suppress lipopolysaccharide-induced interleukin-8 expression in human umbilical vein endothelial cells through blockade of p38 and Akt protein kinases. Acta Pharmacol Sin, 2011; 32(4): 478-86 (IF=5.06).

        (21)Hongtao Liu, Junlin He, Wenming Li, Zhu Yang, Yingxiong Wang, Xuefang Bai, Chao Yu, Yuguang Du. Chitosan oligosaccharides protect human umbilical vein endothelial cells from hydrogen peroxide-induced apoptosis. Carbohydr Polym, 2010; 80(4): 1062–71 (IF=7.18).

        (22)Hongtao Liu, Wenming Li, Pei Huang, Wenjuan Chen, Qishun Liu, Xuefang Bai, Chao Yu, Yuguang Du. Chitosan oligosaccharides inhibit TNF-α-induced VCAM-1 and ICAM-1 expression in human umbilical vein endothelial cells by blocking p38 and ERK1/2 signaling pathways. Carbohydr Polym, 2010; 81(1): 49–56 (IF=7.18).

        (23)Hongtao Liu, Wenming Li, Gang Xu, Xiuying Li, Xuefang Bai, Peng Wei, Chao Yu, Yuguang Du. Chitosan oligosaccharides attenuate hydrogen peroxide-induced stress injury in human umbilical vein endothelial cells. Pharmacol Res, 2009; 59(3): 167–75 (IF=5.89).

        (24)李瑋,李德遠,鄭哲君,胡杰,劉志國,徐冰心. 螺旋藻對四氧化二氮導致的動(dòng)物損傷的防護效應研究.營(yíng)養學(xué)報,2011,35(4):405-410

        (25)易凡琪, 鄭軍平, 李瓊瑜, 焦思明, 杜昱光, 葉云*, 劉洪濤*. 幾丁寡糖對脂肪酸代謝紊亂的抑制作用及分子機制. 生物工程學(xué)報. 2017; 33(7): 1−12.

        亚洲精品色婷婷在线影_在线欧美日韩内地vr_51精品国产人成在线观看_一本精品99久久精品77
        <samp id="fbtor"><video id="fbtor"></video></samp>
      2. <small id="fbtor"></small>
        <ruby id="fbtor"></ruby>
        <ruby id="fbtor"><video id="fbtor"></video></ruby>
      3. <ruby id="fbtor"><table id="fbtor"><b id="fbtor"></b></table></ruby>

        <track id="fbtor"><table id="fbtor"></table></track>
          <strong id="fbtor"></strong> <legend id="fbtor"><font id="fbtor"></font></legend><strong id="fbtor"></strong>
          1. <small id="fbtor"></small>